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Based on its recent analysis of the North American immune health ingredient market, Frost & Sullivan recognizes Kyowa Hakko USA, Inc. (Kyowa Hakko) with the 2021 North American New Product Innovation Award for its clinically backed, patented, non-GMO, allergen-free paraprobiotic, IMMUSE™, Lactococcus lactis strain plasma (LC-Plasma),). The lactic acid bacteria developed by Kirin Holding Company Limited and offered by Kyowa Hakko USA, directly activates immune cells to provide comprehensive innate and adaptive immune support. IMMUSE™ (immusehealth.com) provides ease of formulation and can be used in a number of products including drinks, yogurt, gummies and range of other functional food and beverages.
“IMMUSE™ is backed by twenty-six studies, including 11 human clinical trials that comprise nine efficacy studies and two safety studies, making it one of the most comprehensively studied and clinically validated paraprobiotics ingredients” said Smriti Sharma, Senior Industry Analyst. Also, a series of clinical studies indicates that “IMMUSE™ can improve respiratory health and, in turn, reduces fatigue and enhancessports performance and office productivity”.”Besides, IMMUSE™ has self-affirmed Generally Recognized as Safe (GRAS) status in the United States, positioning it ideally to cater to the growing consumer demand for clean-label functional food and beverages.”
IMMUSE™ provides broad-range immune support by activating plasmacytoid dendritic cells (pDCs). This rare immune cell subset activates other immune cells such as natural killer (NK), killerT, helperT, and B cells, which are important for innate and adaptive immunity. Other immune support ingredients, including generic probiotics and beta-glucan, activate limited immune cell types, imparting only partial immune support compared to IMMUSE™. Dr. Shintaro Ichikawa, Director of Technical Affairs at Kyowa Hakko USA, led the development and product launch of IMMUSE™ notes,“IMMUSE™ is unlike any other immune support ingredient, by activating pDC’s, key leaders of the immune system, IMMUSE™provides more comprehensive immune support.”
Being part of Kirin Holdings, Kyowa Hakko has a distinct edge as it can leverage years of expertise and technical know-how of its parent company. In terms of ensuring higher product quality, the company does not use any organic solvents in the upstream and downstream fermentation processes, making the whole process sustainable. The Lactococcus lactis strain used has a long-established use case history in in cheese and yogurt production. Also, safety studies conducted by Kirin Holdings indicate that the strain is well tolerated even at a high dosage (250 mg/day), which makes IMMUSE™ a safe and reliable immune health ingredient.
“IMMUSE™ has been a part of numerous products such as drinks, yogurt, and other functional food and beverage since its launch, supporting both health and business cases for the ingredient,” noted Sharma. “The strong research associated with the ingredient, its application versatility, and stringent quality standards followed by Kyowa Hakko and its parent group are vital differentiators, and position IMMUSE™ firmly in the competitive immune health space.” We are excited to offer our customers the latest breakthrough approach in immunity as consumers are looking to support their immune systems proactively and consistently with a focus on overall health and wellness year-round. It is an honor to have our innovative Kyowa Hakko clinically-studied ingredient recognized to elevate immune health products.” observes Dr. Shintaro Ichikawa.
Each year, Frost & Sullivan presents this award to the company that has developed an innovative element in a product by leveraging leading-edge technologies. The award recognizes the value-added features/benefits of the product and the increased return on investment (ROI) it gives customers, which, in turn, raises customer acquisition and overall market penetration potential.
Frost & Sullivan Best Practices awards recognize companies in a variety of regional and global markets for demonstrating outstanding achievement and superior performance in areas such as leadership, technological innovation, customer service, and strategic product development. Industry analysts compare market participants and measure performance through in-depth interviews, analysis, and extensive secondary research to identify best practices in the industry.
About Kyowa Hakko USA
Kyowa Hakko USA (Kyowa-USA.com) is the North & South American office for Kyowa Hakko Bio Co. Ltd, an international health ingredients manufacturer and leader in the development, manufacturing, and marketing of pharmaceuticals, nutraceuticals and food products.
About KYOWA HAKKO BIO Co., Ltd
KYOWA HAKKO BIO Co., Ltd is an international ingredients manufacturer whose primary goal is to provide health solutions that support optimal health for improved quality of life. Pioneers in the development and application of innovative fermentation technology, Kyowa’s ingredients meet the most demanding quality assurance standards currently in place within the global dietary supplement, health food, cosmetic and pharmaceuticals industries.
About Kirin Holdings
Kirin Holdings Company, Limited is an international company that operates in the Food & Beverages domain (Food & Beverages businesses), Pharmaceuticals domain (Pharmaceuticals businesses), and Health Science domain (Health Science business), both in Japan and across the globe.
Kirin Holdings can trace its roots to Japan Brewery which was established in 1885. Japan Brewery became Kirin Brewery in 1907. Since then, the company expanded its business with fermentation and biotechnology as its core technologies, and entered the pharmaceutical business in the 1980s, all of which continue to be global growth centers. In 2007, Kirin Holdings was established as a pure holding company and is currently focusing on boosting its Health Science domain.
Under the Kirin Group Vision 2027 (KV 2027), a long-term management plan launched in 2019, the Kirin Group aims to become “A global leader in CSV*, creating value across our world of Food & Beverages to Pharmaceuticals.” Going forward, the Kirin Group will continue to leverage its strengths to create both social and economic value through its businesses, with the aim of achieving sustainable growth in corporate value.
* Creating Shared Value: combined added value for consumers as well as for society at large.
Contact: Maria Stanieich
P: 551-482-9968
E: stanieich[.]kyowa-usa.com.
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lindsey.whitaker[.]frost.com 
