The emerging field of differential mRNA expression analysis using qRT-PCR technologies has given new hope to the search for biomarkers and drug development efforts. The combination of fast analyses with newer multiplexing-capable qRT-PCR instruments has greatly increased the efficiency of the qRT-PCR approach, and it provides users with an invaluable source of data useful for research and clinical purposes.
New analysis from Frost and Sullivan, U.S. qRT-PCR Markets, reveals that the market earned revenues of $586.6 million in 2005 and estimates this market to reach $1229.2 million in 2012.
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Two factors are responsible for growth of the qRT-PCR market: newer qRT-PCR technologies provide an efficient means to simultaneously monitor expression levels of multiple genetic messages in real-time, and qRT-PCR is an extremely cost effective approach. By providing unique access to previously inaccessible information on cellular responses, qRT-PCR has revolutionized the role that genetic technologies play in the healthcare industry.
“qRT-PCR technology makes it possible to spy on the internal communication between cells and their environment,” states Frost & Sullivan Research Analyst Shankar Sellappan, Ph.D. “The proactive approach qRT-PCR market participants have taken with respect to instrument design and reagent optimization has played a significant role in the growth of the market. As the information on how cells respond to stimuli in real-time improves the understanding of fundamental aspects of biological and disease development, strong growth of the qRT-PCR market is expected through 2012.”
Given that the qRT-PCR multiplexing instrument market is relatively new, initial purchases of instruments is likely to drive demand. Furthermore, the need for robust products with enhanced capabilities is likely to offer excellent growth opportunities to smaller market participants in the fragmented qRT-PCR reagents market. For example, market participants have developed thermostable, longer-lasting qRT-PCR reagents that can withstand room temperature for as long as 24 hours, allowing full use of instruments even when laboratory personnel are not present. Manufacturers have responded to demands for lower costs by offering their products at affordable prices to cater to budget-constrained research groups.
“Increased productivity of instruments that incorporate high-throughput technologies such as automated technologies to load samples, robotics to handle reagents, and pathway kits to study disease are driving demand for qRT-PCR reagents,” notes Dr. Sellappan.
Adoption of qRT-PCR by additional users is likely to accelerate market growth as the technology matures. In addition to research uses, new clinical applications incorporating qRT-PCR concepts may provide distinct points in the disease cycle where therapeutic assessment and gene-based therapies, such as siRNA, can be employed.
“Although growth of the qRT-PCR markets reflects improvements in capabilities, emerging microarray technologies offering a higher data per experiment ratio are compelling restraint for qRT-PCR market growth,” cites Dr. Sellappan. “To compete with microarray technologies, this industry must expand the number of targets capable of simultaneous analysis and must develop pathway specific products aimed at providing information on all signals in a related molecular pathway.”
U.S. qRT-PCR Markets is part of the Drug Discovery Technologies subscription, which also includes research in the following markets: mass spectrometry, protein electrophoresis, DNA sequencing, RNAi, microfluidics/lab-on-a-chip, DNA microarrays, and proteomics arrays. All research services included in subscriptions provide detailed market opportunities and industry trends evaluated following extensive interviews with market participants. Interviews are available to the press.
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