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Discover Medical Devices Announces Intermediary Results of its Second Clinical Trial - Discover Medical Devices SomnuSeal masks line successfully addresses the problem of non compliance in Obstructive Sleep Apnea patients - DiscoverMedical.com
Discover Medical Devices Announces Intermediary Results of its Second Clinical Trial

 

PRZOOM - /newswire/ - Givataym, Israel, 2011/06/05 - Discover Medical Devices SomnuSeal masks line successfully addresses the problem of non compliance in Obstructive Sleep Apnea patients - DiscoverMedical.com.

   
 
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Discover Medical Devices announces intermediary results of its second clinical trial with the revolutionary self adaptable intra oral CPAP mask – the SomnuSeal.

The novel SomnuSeal masks do not suffer from the side effects of traditional masks and therefore will allow many millions of OSA patients that currently refuse treatment to receive an effective treatment.

“SomnuSeal will offer a reprieve for more than 5 Million non-compliant, diagnosed OSA patients as well as to the hundreds of thousands newly diagnosed every year.” Says Eran Lavi, Discover Medical’s CEO. “non-compliant patients can’t tolerate currently available treatments. SomnuSeal will enable them to use CPAP treatment and this may end up saving life”

Clinical trial summary:
The SomnuSeal oral mask is tolerated by otherwise CPAP non compliant patients with OSA.
By Giora Pillar, Adi Segev, Eytan Kurtz.
June 2011

Background: Compliance with CPAP is the major limiting factor in treating patients with OSA. Nasal masks may cause skin abrasions or eruptions, mask pressure on the ridge of nose, air leaks (eye discomfort), claustrophobia and nasal stuffiness. The novel SomnuSeal mask is an oral self-adaptable mask located between the teeth and the lips, ensuring no air leaks or skin abrasions. It is more comfortable, adjusts better to the patient’s specific anatomical structure, and potentially reduces rejection by claustrophobic patients. In a previous study, a mixed sample of 20 patients with OSA had slept with the SomnuSeal oral mask for an average of 1 week.

Aim: To evaluate the efficacy and compliance/tolerability of the SomnuSeal oral mask for a one month treatment period in otherwise non-compliant (untreated) patients with moderate-severe OSA.

Methods: So far, 11 patients with RDI>20 had tried the mask for one month. In all patients the mask was connected to an AutoPAP machine with a heated humidifier. Efficacy (respiratory indices), convenience (questionnaire) and compliance (usage meter) were monitored in all patients.

Results: Eleven patients (all males, age 55±15 years, BMI 34.1±5.2 Kg/m2, RDI 48±22/h) have tried the treatment so far. Of them, 4 were satisfied and complied well with it (for an average of 26 nights, 5.1 hours per night), 3 struggled with it (used it for an average of 13 nights, 3.3 hours per night), and 4 could not comply with it. In all patients who slept with it, the efficacy (assessed by residual RDI derived from the CPAP device) was good, with an RDI of less than 5/hour. Interestingly, the required optimal pressure decreased from an average of 9.9cmH2O to 5.2cmH2O.

Conclusions: The SomnuSeal oral interface is effective, and may result in converting non-compliant untreated patient with OSA into well treated ones. In the current preliminary experiment, 4 of 11 patients (36%) who were CPAP non-compliant and remained otherwise untreated, were satisfied and well tolerated the SomnuSeal mask, while additional 3 patients (27%) struggled with it and may have ended up being treated. These results are encouraging to offer this mask and reduce the currently high prevalence of CPAP non-compliant untreated patients with OSA.

For more information visit discovermedical.com/.

 
 
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Discover Medical Devices Announces Intermediary Results of its Second Clinical Trial

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Contact: Eran Lavi - DiscoverMedical.com 
+972 522649047 info[.]discovermedical.com
 
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