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AnaSpec Launches New SensoLyte® Rh110 Long Wavelength Plasmin Activity Assay Kit - AnaSpec is pleased to announce the release of another long wavelength protease assay – the SensoLyte® Rh110 Plasmin Activity Assay Kit (Ex/Em=496 nm/520 nm)
AnaSpec Launches New SensoLyte® Rh110 Long Wavelength Plasmin Activity Assay Kit

 

PRZOOM - /newswire/ - San Jose, CA, United States, 2009/03/12 - AnaSpec is pleased to announce the release of another long wavelength protease assay – the SensoLyte® Rh110 Plasmin Activity Assay Kit (Ex/Em=496 nm/520 nm).

   
 
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AnaSpec, known for developing sensitive, long wavelength assays, is pleased to announce the release of another long wavelength protease assay – the SensoLyte® Rh110 Plasmin Activity Assay Kit (Ex/Em=496 nm/520 nm).

Plasmin is a serine protease derived from the conversion of plasminogen in blood plasma by plasminogen activators.1 Its primary function is to degrade fibrin in blood clots.1 Plasmin activators and inhibitors are thought to be the key participants in the balance between proteolytic and antiproteolytic activities that regulate extracellular matrix degradation.2 In addition to its established role in fibrinolysis, plasmin is also involved in several pathological and physiological processes such as embryogenesis, ovulation, inflammation, wound healing, angiogenesis, neoplasia, and metastasis.2

The SensoLyte® Rh110 Plasmin Assay Kit provides a convenient assay for screening of enzyme inhibitors and activators or for continuous assay of enzyme activity using a fluorogenic substrate. Upon plasmin protease cleavage, this substrate generates the Rh110 (rhodamine 110) fluorophore which has a bright green fluorescence and can be detected at Ex/Em=496 nm/520 nm. The longer-wavelength spectra and higher extinction coefficient of the Rh110 provide greater sensitivity and less interference from other reaction components.

About AnaSpec

AnaSpec (anaspec.com) is a leading provider of integrated proteomics solutions to the world’s largest biotech, pharmaceutical, and academic research institutions. With a vision for innovation through synergy, AnaSpec focuses on three core technologies: peptides, detection reagents, and combinatorial chemistry.

References:
1. Collen, D. Circulation, 93, 857 (1996).
2. Vassalli, J.D. et al, J. Clin. Invest. 88, 1067 (1991).

 
 
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AnaSpec Launches New SensoLyte® Rh110 Long Wavelength Plasmin Activity Assay Kit

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Contact: Ping Yang 
408-452-5055 ping[.]anaspec.com
 
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IMPORTANT INFORMATION: Issuance, publication or distribution of this press release in certain jurisdictions could be subject to restrictions. The recipient of this press release is responsible for using this press release and the information herein in accordance with the applicable rules and regulations in the particular jurisdiction. This press release does not constitute an offer or an offering to acquire or subscribe for any AnaSpec, Inc. securities in any jurisdiction including any other companies listed or named in this release.

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