PRZOOM - /newswire/ -
San Jose, CA, United States, 2008/10/14 - Thermo Fisher Scientific Inc., the world leader in serving science, today announced the launch of MetWorks 1.2, an updated version of its successful metabolite identification software.
Thermo Scientific MetWorks is a powerful data-mining tool for small molecules that can be used to search for and identify a variety of metabolites with a high degree of accuracy and confidence. Thermo Fisher will showcase the newest capabilities of MetWorks at the 15th North American Regional ISSX Meeting in San Diego, California on October 12-16, 2008.
MetWorks facilitates the acquisition, processing and reporting of liquid chromatography/mass spectrometry data. Dr. Yingying Huang, strategic marketing specialist for the metabolism and metabolomics group at Thermo Fisher Scientific, explains: "Thanks to a range of new features, the latest version of the software will dramatically simplify and speed up the search for expected and unexpected biotransformations."
MetWorks 1.2 boasts a new graphical user interface (GUI) that exploits the power of multiple mass defect filters (MMDF). Mass defect filtering is one of the most powerful and sophisticated ways of using high-resolution mass data to obtain a smaller, more refined data set for review. The interactive MMDF GUI displays the distribution of parent and potential metabolites and allows both novice and expert users to mine the data in a quick and easy manner. Combined with high-resolution data from a Thermo Scientific LTQ Orbitrap mass spectrometer, MetWorks facilitates extraction of low levels of metabolite ions, even when they are three to four orders of magnitude less abundant than the background matrix ions, thus providing a significantly enhanced signal-to-noise ratio.
This latest version of the software also features a new concise summary report that conforms to industry standards, as well as provides accurate mass analysis data (with ppm values). Additionally, there are new Analyte and Modification Managers which automatically calculate accurate masses for parent compounds and potential biotransformations using standard molecular formulae.
MetWorks software is compatible with all Thermo Scientific mass spectrometers capable of performing MS/MS and MSn fragmentation. It takes advantage of reproducible MSn fragmentation data and enables analysis of high-resolution accurate mass data, available from the Thermo Scientific LTQ Orbitrap hybrid mass spectrometer and LTQ FTTM Fourier transform instruments, to be fully exploited.
As Dr. Huang explains, "MetWorks 1.2 is powerful, easy to use and provides confident and accurate results in less time. This enables researchers and developers working in the pharmaceutical industry to streamline the drug discovery and development processes. They will find this tool invaluable."
For more information on Thermo Scientific MetWorks software, as well as other Thermo Scientific products, please visit Thermo Scientific booth 1 at the 15th North American Regional ISSX Meeting in San Diego on October 12-16.
Thermo Scientific is part of Thermo Fisher Scientific, the world leader in serving science.
About Thermo Fisher Scientific
Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in serving science, enabling our customers to make the world healthier, cleaner and safer. With annual revenues of $10 billion, we have more than 30,000 employees and serve over 350,000 customers within pharmaceutical and biotech companies, hospitals and clinical diagnostic labs, universities, research institutions and government agencies, as well as environmental and industrial process control settings. Serving customers through two premier brands, Thermo Scientific and Fisher Scientific, we help solve analytical challenges from routine testing to complex research and discovery. Thermo Scientific offers customers a complete range of high-end analytical instruments as well as laboratory equipment, software, services, consumables and reagents to enable integrated laboratory workflow solutions. Fisher Scientific provides a complete portfolio of laboratory equipment, chemicals, supplies and services used in healthcare, scientific research, safety and education. Together, we offer the most convenient purchasing options to customers and continuously advance our technologies to accelerate the pace of scientific discovery, enhance value for customers and fuel growth for shareholders and employees alike.
For further press information please contact: Laura Browne, The Scott Partnership, 1 Whiteside, Station Road, Holmes Chapel, Cheshire. CW4 8AA United Kingdom T: +44 1477 539539 F: +44 1606 1477 539540 E: thermo[.]scottpr.com.