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AnaSpec Introduces Collection of Channel Blocker Peptides - AnaSpec has introduced its selection of channel blocker peptides
AnaSpec Introduces Collection of Channel Blocker Peptides

 

PRZOOM - /newswire/ - San Jose, CA, United States, 2008/02/19 - AnaSpec has introduced its selection of channel blocker peptides.

   
 
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Peptide toxins are potent and selective compounds that can act on ion channels in plasma membrane of excitable cells.1 These high specificity and affinity compounds, often with diverse and selective pharmacologies, are used as pharmacological probes to study and characterize various receptor proteins involved in ion-channel function.1 These toxin peptides generally consist of a relatively small number of structural frameworks that are particularly suited to addressing the crucial issues of potency and stability.1 Multiple disulfide bonds constitute essential structural elements in many of these bio-active peptides, which are generated by proteolytic processing of pre-folded protein precursors and then released from the cells in the bio-active form into the extracellular medium to exert their physiological function.

Ca2+ Channel Blockers
ω-Conotoxin GVIA
ω-Conotoxin MVIIC
ω-Conotoxin MVIIA
Imperatoxin A (IpTxa)
Ryanodine receptor agonist

K+ Channel Blockers
Iberiotoxin (IbTX)
Charybdotoxin
[Glu32]-Charybdotoxin
Apamin
Mast Cell Degranulating Peptide, MCD

Cl-Channel Blocker
Chlorotoxin (Cltx)

Other Ion Channel Blockers
Conantokin G
Sarafotoxin 6C
[Lys4]-Sarafotoxin 6c
Beauvericin

About AnaSpec, Inc.
AnaSpec, Inc. is a leading provider of integrated proteomics solutions to pharmaceutical, biotech, and academic research institutions throughout the world. With a vision for innovation through synergy, AnaSpec focuses on three core technologies: peptides, detection reagents (dyes, assay kits, & antibodies), and combinatorial chemistry.

Reference:
1. Lewis, RJ. and ML. Garcia, Nat. Rev. Drug Discov. 2, 790 (2003)

 
 
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AnaSpec Introduces Collection of Channel Blocker Peptides

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Contact: Ping Yang 
408-452-5055 ping[.]anaspec.com
 
PRZOOM / PRTODAY - Newswire Today disclaims any content contained in this article. If you need/wish to contact the company who published the current release, you will need to contact them - NOT us. Issuers of articles are solely responsible for the accuracy of their content. Our complete disclaimer appears here.
IMPORTANT INFORMATION: Issuance, publication or distribution of this press release in certain jurisdictions could be subject to restrictions. The recipient of this press release is responsible for using this press release and the information herein in accordance with the applicable rules and regulations in the particular jurisdiction. This press release does not constitute an offer or an offering to acquire or subscribe for any AnaSpec, Inc. securities in any jurisdiction including any other companies listed or named in this release.

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