Free press releases distribution network?

Agency / Source: GTCbio - Biopharmaceutical Conference

Check Ads Availability|e-mail Article


Are you the owner of this article?, Turn it PREMIUM with your LOGO instead - and make it 3rd party Ads-Free! within the next hour!



Biogen-Idec to Present at GTCbio’s 6th Cytokines and Inflammation January 28-29, 2008 - Shelia Violette, Director of Discovery Immunology at Biogen-Idec will give a presentation entitled “The Alphavbeta6 Integrin: A Mediator of TGF-Beta Activation and Therapeutic Target in Fibrosis and Oncology” at GTCbio’s 6th Cytokines
Biogen-Idec to Present at GTCbio’s 6th Cytokines and Inflammation January 28-29, 2008

 

PRZOOM - /newswire/ - Monrovia, CA, United States, 2008/01/14 - Shelia Violette, Director of Discovery Immunology at Biogen-Idec will give a presentation entitled “The Alphavbeta6 Integrin: A Mediator of TGF-Beta Activation and Therapeutic Target in Fibrosis and Oncology” at GTCbio’s 6th Cytokines.

   
 
Your Banner Ad Here instead - Showing along with ALL Articles covering Pharma/BioTech/Nutrition Announcements

Replace these Affiliate Programs at ANYTIME! Your banner here within the next hour. Learn How!


 

Shelia Violette, Director of Discovery Immunology at Biogen-Idec will give a presentation entitled “The Alphavbeta6 Integrin: A Mediator of TGF-Beta Activation and Therapeutic Target in Fibrosis and Oncology” at GTCbio’s 6th Cytokines and Inflammation (January 28-29, 2008, Orlando, Florida.

The avb6 integrin is expressed at low levels in healthy adult tissue and significantly upregulated, mainly on epithelial cells, in fibrotic disease and carcinomas. avb6 binds and activates the latent precursor form of TGF-b and mediates interactions with matrix proteins. TGF-b is central to the initiation and maintenance of fibrosis, a pathological process marked by the replacement of diseased tissue with excess extracellular matrix and ultimately leading to organ scarring and failure. This cytokine is also implicated in promoting tumor progression, and metastases.

Biogen-Idec evaluated avb6 expression in human disease and in preclinical animal models. avb6 is highly upregulated in lung and kidney disease associated with fibrotic pathology, and in liver disease associated with acute biliary duct injury. It is also highly upregulated in squamous cell carcinomas and metastatic lesions, with expression often predominant at the tumor-stromal interface reflecting a unique mechanism for localized TGF-b activation promoting tumor growth and invasion. Biogen-Idec generated potent and selective blocking avb6 antibodies, and tested their ability to inhibit fibrosis and tumor progression in animal models. These antibodies have potent anti-fibrotic activity and inhibit tumor progression in multiple models of disease. A lead clinical candidate antibody has been selected and humanized. Biogen-Idec findings support a role for avb6 in fibrosis and tumor progression and the potential for therapeutic intervention with a function blocking antibody. This approach provides an opportunity to locally inhibit TGF-b and minimize the potential for tumor promoting and pro-inflammatory activity that may be associated with systemic blockade of the TGF-b pathway.

The conference also features presentations from other leading organizations such as Amgen, AstraZeneca, FDA, Genentech, Merck, NIH, Novo Nordisk, Pfizer, Roche, Schering Plough, and many more. The full agenda is available online.

GTCbio’s 6th Cytokines and Inflammation conference will take place on January 28-29, 2008 at the Orlando Metropolitan Resort in Orlando, Florida and will cover Cytokines Signaling and Regulation, Inflammation and Cancer, Technological Developments in Cytokines Biology, Chemokines, and Targeting of Cytokine Receptors

About GTCbio

GTCbio organizes conferences specifically for the biomedical and biopharmaceutical industries. Our goal is to facilitate the exchange of biopharmaceutical and biomedical intelligence between industry leaders, academic and government organizations, and the financial community.

GTCbio is a subsidiary of Global Technology Community, LLC, a privately held company founded in 2002.

 
 
Your Banner Ad Here instead - Showing along with ALL Articles covering Pharma/BioTech/Nutrition Announcements

Replace these Affiliate Programs at ANYTIME! Your banner here within the next hour. Learn How!


 

Agency / Source: GTCbio - Biopharmaceutical Conference

 
 

Availability: All Regions (Including Int'l)

 

Traffic Booster: [/] Quick PRZOOM - Press & Newswire Visibility Checker

 

Distribution / Indexing: [+]

 
 
# # #
 

 
  Your Banner Ad showing on ALL
Pharma/BioTech/Nutrition articles,
CATCH Visitors via Your Competitors Announcements!


Biogen-Idec to Present at GTCbio’s 6th Cytokines and Inflammation January 28-29, 2008

Company website links NOT available to basic submissions
It is OK to republish and/or LINK any newswire for any legitimate media purpose as long as you name PRZOOM - Press & Newswire and LINK as the source.
 
  For more information, please visit:
Is this your article? Activate ALL web links by Upgrading to Press Release PREMIUM Plan Now!
|
Contact: Rania Hafez 
(626) 256-6405 raniah[.]gtcbio.com
 
PRZOOM / PRTODAY - Newswire Today disclaims any content contained in this article. If you need/wish to contact the company who published the current release, you will need to contact them - NOT us. Issuers of articles are solely responsible for the accuracy of their content. Our complete disclaimer appears here.
IMPORTANT INFORMATION: Issuance, publication or distribution of this press release in certain jurisdictions could be subject to restrictions. The recipient of this press release is responsible for using this press release and the information herein in accordance with the applicable rules and regulations in the particular jurisdiction. This press release does not constitute an offer or an offering to acquire or subscribe for any GTCbio - Biopharmaceutical Conference securities in any jurisdiction including any other companies listed or named in this release.

Pharma/BioTech/Nutrition via RSSAdd NewswireToday - PRZOOM Headline News to FeedBurner
Find who RetweetFollow @NewswireTODAY



Are you the owner of this article?, Turn it PREMIUM with your LOGO instead - and make it 3rd party Ads-Free! within the next hour!




Read Latest Press Releases From GTCbio - Biopharmaceutical Conference / Company Profile


Read Pharma/BioTech/Nutrition Most Recent Related Press Releases:

MDxHealth Signs Agreement with Lab21 to Make SelectMDx Liquid Biopsy Test Available in the United Kingdom
Greenphire Drives Global Site Adoption of Clinical Trial Payment Solutions
SelectMDx Chosen by Michigan Medicine as Pre-biopsy Diagnostic Tool in Groundbreaking US Prostate Cancer Risk Clinic
BTG Announces CE Mark Certification for DC Bead LUMI™ - The First Commercially Available Radiopaque Drug-Eluting Bead
Sartorius to Acquire Real-time Live-cell Analysis Pioneer and Leader Essen BioScience
Pyxis™ ES System to Help U.S. Department of Defense Advance Medication Safety and Patient Care
BTG Receives U.S. FDA 510(k) Clearance for EKOS® Control Unit 4.0
MDxHealth Announces Agreement with Istituto Diagnostico Varelli for Distribution of SelectMDx Throughout Central-South Italy
BD Veritor™ System Meets FDA’s New Performance Requirements for Rapid Influenza Antigen Detection Tests
Sub-Sahara Africa - Increase in Western Lifestyles Leads to Dire Need for Chronic Prescription Drugs Finds Frost & Sullivan

Boost Your Social Network
& Crowdfunding Campaigns


LIFETIME SOCIAL MEDIA WALL
 
NewswireToday Celebrates 10 Years in Business
Find business coaching, life coaching, executive coaching and corporate coaching, best selling coaching books, ...



PREMIUM Members


Visit  MagLar, Inc.

Visit  La Bella Bakery Artisan Bakery Arizona

Visit  JobsWare.com







 
  ©2017 PRZOOM — Limelon Advertising, Co.
Home | About PRZOOM | Advertise/Pricing | Contact | Investors | Privacy/TOS | Sitemap | FRANCAIS
newswire, PR free press releases distribution service magazines engine news alert newsroom press room breaking news public relations articles company news alerts newswiredistribution ezine bizentrepreneur biznewstoday digital business report market search pr firms agencies reports distri-bution today investor relation successful internet entrepreneur newswire distribution prtoday.com freenewswiredistribution asianewstoday bizwiretoday USA pr UK today