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First Pulmonary Embolism Patients in Hong Kong Treated with the EKOS® System - BTG plc, the global specialist healthcare company, today announced the first patients diagnosed with Pulmonary Embolism (PE) to be treated in Hong Kong using the newly available EKOS® system - BTGplc.com
First Pulmonary Embolism Patients in Hong Kong Treated with the EKOS® System

 

PRZOOM - /newswire/ - Farnham, Surrey, United Kingdom, 2017/01/10 - BTG plc, the global specialist healthcare company, today announced the first patients diagnosed with Pulmonary Embolism (PE) to be treated in Hong Kong using the newly available EKOS® system - BTGplc.com. LSE: BTG

   
 
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The EKOS® system includes an ultrasonic device that uses acoustic pulses to quickly and safely dissolve blood clots and restore blood flow in patients with PE, deep vein thrombosis (DVT), and peripheral arterial occlusions (PAO).

Blood clots are tightly bound together in a fibrous mesh called fibrin. Fibrin blocks the flow of thrombolytic drugs, requiring a higher drug dose to be effective.The EKOS®system uses acoustic pulses to unwind and thin fibrin to expose drug receptor sites, allowing the drug to reach deeper into the clot, accelerating absorption and helping to dissolve the clot faster and with less thrombolytic.1,2

Dr. Luk Wing Hang, Consultant Radiologist at the Princess Margaret Hospital, who performed the procedure on one of the patients, said: “Prevalence of fatal PE was 0.21% (1964-74), 1.08% (1975-79), 1.83% (1980-84), 2.77% (1985-90), and 4.7% (1990- 94) and the trend has been found to be increasing year after year with the percentage approaching western countries’ occurrence rate”. In addition, Dr. Luk updated that the patient treated with the EKOS® system was clinically stabilized with no desaturation or shortness of breath and their blood pressure was back to normal.

Later, in the same week, another case of submassive pulmonary embolism was treated just eight miles away at the Prince of Wales Hospital, where Interventional Cardiologist Prof. Bryan P. Yan was the treating physician. “The EKOS® system enables much lower and safer doses of thrombolytic drugs to be used which significantly reduces the risk of major bleeding. The device is currently the only US FDA cleared, minimally invasive endovascular therapy for PE” Our patient’s condition was improved significantly after 12 hours of ultrasound assisted thrombolysis with the EKOS® system. His breathing and blood pressure were improved and his grossly dilated right heart returned to nearly normal size and he was successfully discharged home” added Prof. Bryan P. Yan.

James Glasgow, General Manager at BTG Asia, said: “I am pleased to introduce our ultrasonic catheter device to the Hong Kong market to improve the treatment of severe blood clots. BTG is committed to delivering a better standard of care for patients who suffer from PE, DVT and PAO, with improved outcomes and lower associated risks through the development of minimally invasive therapies like the EKOS® system.”

The EKOS® system is now commercially available to hospitals in Hong Kong. The EKOS®system is distributed in Hong Kong by PPL Medical Limited which has the rich experience of distributing life-saving medical devices and equipment in Hong Kong and Macau for over 35 years.

About Pulmonary Embolism
Pulmonary Embolism (PE) is a condition where one or more clots break off or travel from existing venous clots in the legs or arms and travel in the circulation, getting trapped in the lung, where they block the ability of blood to get to some areas of the lungs and receive oxygen. This may lead to a strain on the heart’s ability to pump blood through the lungs which can then lead to heart failure and/or cardiovascular collapse. PEs can be immediately fatal, but if PE can be diagnosed and appropriate therapy started, the mortality can be reduced from approximately 30 percent to less than 10 percent.7

About the EkoSonic® Endovascular System
The EKOS® system uses ultrasonic waves in combination with clot-dissolving thrombolytic drugs to effectively dissolve clots and restore healthy heart function and blood flow.

In clinical studies EKOS®therapy has been shown to speed time-to-clot dissolution, increase clot removal and enhance clinical improvement compared to either standard catheter-directed drug therapy or thrombectomy.4,5EKOS®therapy requires significantly shorter treatment times and less thrombolytic compared to standard catheter-directed drug therapy6, lowering the risk of bleeding and other complications.2,3

Reference materials as the remarks in the press release:

1. Chau KY, Yuen ST, Ng TH, Ng WF. An autopsy study of pulmonary thromboembolism in Hong Kong Chinese. Pathology 1991;23:181-4. Chau KY, Yuen ST, Wong MP. Clinicopathological pattern of pulmonary thromboembolism in Chinese autopsy patients: comparison with Caucasian series. Pathology 1997;29:263-6.
2. Kucher, N., et al.,“Randomized, Controlled Trial of Ultrasound-Assisted Catheter-Directed Thrombolysis for Acute Intermediate-Risk Pulmonary Embolism.” Circulation, Vol. 129, No. 4, 2014, 479 486.
3. Piazza G et al. A Prospective, Single-Arm, Multicenter Trial of Ultrasound-Facilitated, Catheter-Directed, Low-Dose Fibrinolysis for Acute Massive and Submassive Pulmonary Embolism. The SEATTLE II Study. J Amer Coll Cardiol: Cardiovasc Interventions 2015; 8(10):1382-1392.
4. Lin, P., et al.,“Comparison of Percutaneous Ultrasound-Accelerated Thrombolysis versus Catheter-Directed Thrombolysis in Patients with Acute Massive Pulmonary Embolism.” Vascular, Vol. 17, Suppl. 3, 2009, S137 S147.
5. Lin, P., et al.,“Catheter-Directed Thrombectomy and Thrombolysis for Symptomatic Lower-Extremity Deep Vein Thrombosis: Review of Current Interventional Treatment Strategies.” Perspectives in Vascular Surgery and Endovascular Therapy, 2010, 22(3): 152 163.
6. Parikh, S., et al.,“Ultrasound-Accelerated Thrombolysis for the Treatment of Deep Vein Thrombosis: Initial Clinical Experience.” Journal of Vascular and Interventional Radiology, Vol. 19, Issue 4, April 2008, 521 528.
7. Banovac, R et al., J Vasc Interv Radiol, 2010; 21:44-53.

Contactd:
Chris Sampson, Corporate Communications Director
P: +44(0)20 7575 1595 / M: +44 (0)77 7325 1178

Greentarget Communications: Chris Gale, Vice President
P: +1 646-695-2883 / M: +1 203-570-4681

About BTG
BTG (btgplc.com) is a global specialist healthcare company bringing to market innovative products in specialist areas of medicine to better serve doctors and their patients. We have a portfolio of Interventional Medicine products to advance the treatment of cancer, severe emphysema, severe blood clots and varicose veins, and Specialty Pharmaceuticals that help patients overexposed to certain medications or toxins. Inspired by patient and physician needs, BTG is investing to expand its portfolio to address some of today’s most complex healthcare challenges.

 
 
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First Pulmonary Embolism Patients in Hong Kong Treated with the EKOS® System

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EKOS® System | BTG plc
Contact: Hayley Senior - BTGplc.com 
+44(0)20 7575 1582 / +44(0)78 1577 8536 (mobile)
 
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