Free press releases distribution network?

Agency / Source: Frost & Sullivan

Check Ads Availability|e-mail Article


Are you the owner of this article?, Turn it PREMIUM with your LOGO instead - and make it 3rd party Ads-Free! within the next hour!



Frost & Sullivan Highlights argenx for Enhancing the Therapeutic Qualities of Human Antibodies with its Proprietary Antibody Discovery Platform, SIMPL - argenx’s specific drug candidates include ARGX-113 for myasthenia gravis, ARGX-110 for cancer immunotherapy, and ARGX-111 for c-MET - argenx.com / Frost.com
Frost & Sullivan Highlights argenx for Enhancing the Therapeutic Qualities of Human Antibodies with its Proprietary Antibody Discovery Platform, SIMPL

 

PRZOOM - /newswire/ - London, United Kingdom, 2016/10/05 - argenx’s specific drug candidates include ARGX-113 for myasthenia gravis, ARGX-110 for cancer immunotherapy, and ARGX-111 for c-MET - argenx.com / Frost.com.

   
 
Your Banner Ad Here instead - Showing along with ALL Articles covering Pharma/BioTech/Nutrition Announcements

Replace these Affiliate Programs at ANYTIME! Your banner here within the next hour. Learn How!


 

Based on its recent analysis of the therapeutic antibody engineering market, Frost & Sullivan recognises argenx N.V. with the 2016 European Frost & Sullivan Award for Technology Innovation. argenx’s SIMPLE Antibody™ discovery platform is a huge improvement on conventional antibody discovery platforms because it yields an unprecedented epitope coverage, allowing to interact with the disease biology in a much more precise manner. The application diversity of the platform enables it to generate a wide array of antibodies for different types of cancer and autoimmune disorders.

Significantly, argenx developed its proprietary antibodies by assessing the VH and VL domains found in the Camelidae family. Unlike chimeric antibodies, an extensive structural homology is present between the hypervariable loops of the VH and VL domains found in camelids and the ones found in humans. These rather surprising, yet unique, aspects of conventional antibodies from Camelidae have allowed argenx to engineer them into therapeutic antibodies.

“argenx’s ‘humanised’ monoclonal antibody can minimise the immunogenicity of the drug in the patient, the platform can be used to create a host of unique therapeutic antibodies for disease areas that currently lack treatment options” said Frost & Sullivan Research Analyst Madhumitha Rangesa. “One of the main application areas of argenx’s antibodies is cancer, and it has already achieved an impressive degree of success through therapeutic classes such as cancer immunotherapies.”

argenx’s leading drug candidates in cancer therapy include the ARGX-110, a SIMPLE Antibody™ specifically used for T-cell lymphoma (TCL), renal cell carcinoma, ovarian cancer, and mesothelioma. While ARGX-110 has presented promising safety profiles in these solid tumour and blood cancer indications, it is mainly aimed at TCL.

The next drug candidate is ARGX-111, which is mainly meant for MET amplified cancers. argenx is also working on the ARGX-115 for a variety of cancer indications and the ARGX-113, which is only being used for the treatment of autoimmune disorders (specifically orphan diseases such as systemic lupus and myasthenia gravis). All these drug candidates are still in the early pipeline phase. Through its partnered projects, the application areas have expanded from cancer immunotherapy and autoimmune diseases to skin inflammation.

“Another visionary innovation by argenx is a series of Fc engineering complementary technology platforms such as NHance®. This proprietary approach is associated with specific mutations that are present in the Fc region of the antibody,” noted Rangesa. “NHance® can potentially prolong a typical half-life and thereby, reduce the dosage requirements for the patient, making the entire treatment more cost-effective and shorter. NHance® does not affect the immunogenicity and the ease of manufacturing of the antibodies, ensuring there are no adverse effects due to its use.”

Similarly, argenx’s ABDEG™ technology focuses on a known mechanism that enhances immunoglobulin G (IgG) recycling. By re-engineering the Fc region of IgG, the activity of the neonatal Fc receptor (FcRn) that gets bound to the IgG can have a higher affinity and a lack of pH dependence on FcRn. This reduces the IgG levels, and is highly effective when used in diseases that are mediated through IgG levels. This way, IgG can be cleared from the patient through the antibodies that are created to treat them.

The company’s intellectual property covers its lead ARGX-110 and ARGX-111 drug candidates. The projection for patent expiry is currently 2032, with a five-year patent term extension, giving the company opportunities to effectively market its future drug candidates.

Additionally, the superior quality of the platform and capabilities of the antibodies have attracted partnerships from leading pharmaceutical companies. It has employed a joint risk model with Abbvie, Leo Pharmaceuticals, Shire, and Bayer to support antibody therapeutics. argenx has also designed a unique business model called the Innovative Access Program (IAP), through which it has been pushing the frontiers in the space of cancer immunotherapy.

Overall, with the launch of its cutting-edge SIMPLE Antibody™ technology, argenx has raised the bar for innovation in the therapeutic antibody engineering market.

Each year, Frost & Sullivan presents this award to the company that has demonstrated uniqueness in developing and leveraging new technologies, which significantly impacts both the functionality and the customer value of the new products and applications. The award lauds the high R&D spent towards innovation, its relevance to the industry, and the positive impact on brand perception.

Frost & Sullivan Best Practices awards recognise companies in a variety of regional and global markets for demonstrating outstanding achievement and superior performance in areas such as leadership, technological innovation, customer service, and strategic product development. Industry analysts compare market participants and measure performance through in-depth interviews, analysis, and extensive secondary research to identify best practices in the industry.

About argenx N.V.
argenx (argenx.com) combines the diversity of the llama immune system with antibody engineering to advance a clinical pipeline to treat patients with cancer and autoimmune diseases. Our platforms allow us to unlock novel and complex targets and develop antibody-based drugs designed for greater efficacy and longer duration of effect. The strength of our team, our deep understanding of the biology, and our committed collaborations with industry leaders contribute to the success of our journey. argenx is listed on the Euronext Brussels exchange under the symbol ARGX.

About Frost & Sullivan
Frost & Sullivan (frost.com), the Growth Partnership Company, works in collaboration with clients to leverage visionary innovation that addresses the global challenges and related growth opportunities that will make or break today's market participants.

Our “Growth Partnership” supports clients by addressing these opportunities and incorporating two key elements driving visionary innovation: The Integrated Value Proposition and The Partnership Infrastructure.

The Integrated Value Proposition provides support to our clients throughout all phases of their journey to visionary innovation including: research, analysis, strategy, vision, innovation and implementation.

The Partnership Infrastructure is entirely unique as it constructs the foundation upon which visionary innovation becomes possible. This includes our 360 degree research, comprehensive industry coverage, career best practices as well as our global footprint of more than 40 offices.

For more than 50 years, we have been developing growth strategies for the global 1000, emerging businesses, the public sector and the investment community. Is your organisation prepared for the next profound wave of industry convergence, disruptive technologies, increasing competitive intensity, Mega Trends, breakthrough best practices, changing customer dynamics and emerging economies?

Contact Us: Start the discussion | Join Us: Join our community | Subscribe: Newsletter on "the next big thing" | Register: Gain access to visionary innovation.

 
 
Your Banner Ad Here instead - Showing along with ALL Articles covering Pharma/BioTech/Nutrition Announcements

Replace these Affiliate Programs at ANYTIME! Your banner here within the next hour. Learn How!


 

Agency / Source: Frost & Sullivan

 
 

Availability: All Regions (Including Int'l)

 

Traffic Booster: [/] Quick PRZOOM - Press & Newswire Visibility Checker

 

Distribution / Indexing: [+] / [Company listed above is a registered member of our network. Content made possible by PRZOOM / PRTODAY indexing services]

 
 
# # #
 

 
  Your Banner Ad showing on ALL
Pharma/BioTech/Nutrition articles,
CATCH Visitors via Your Competitors Announcements!


Frost & Sullivan Highlights argenx for Enhancing the Therapeutic Qualities of Human Antibodies with its Proprietary Antibody Discovery Platform, SIMPL

Company website links NOT available to basic submissions
It is OK to republish and/or LINK any newswire for any legitimate media purpose as long as you name PRZOOM - Press & Newswire and LINK as the source.
 
  For more information, please visit:
Is this your article? Activate ALL web links by Upgrading to Press Release PREMIUM Plan Now!
Frost & Sullivan | argenx N.V.
Contact: Chiara Carella - Frost.com 
+44(0)20 7343 8314 chiara.carella[.]frost.com
 
PRZOOM / PRTODAY - Newswire Today disclaims any content contained in this article. If you need/wish to contact the company who published the current release, you will need to contact them - NOT us. Issuers of articles are solely responsible for the accuracy of their content. Our complete disclaimer appears here.
IMPORTANT INFORMATION: Issuance, publication or distribution of this press release in certain jurisdictions could be subject to restrictions. The recipient of this press release is responsible for using this press release and the information herein in accordance with the applicable rules and regulations in the particular jurisdiction. This press release does not constitute an offer or an offering to acquire or subscribe for any Frost & Sullivan securities in any jurisdiction including any other companies listed or named in this release.

Pharma/BioTech/Nutrition via RSSAdd NewswireToday - PRZOOM Headline News to FeedBurner
Find who RetweetFollow @NewswireTODAY



Are you the owner of this article?, Turn it PREMIUM with your LOGO instead - and make it 3rd party Ads-Free! within the next hour!




Read Latest Press Releases From Frost & Sullivan / Company Profile


Read Pharma/BioTech/Nutrition Most Recent Related Press Releases:

Genentech’s Gazyva Helped People with Previously Untreated Follicular Lymphoma Live Significantly Longer
BD Announces Adoption of Windows 10 ‘Internet of Things’ for the Pyxis™ ES System
Greenphire Named to Deloitte 2016 Technology Fast 500™
Genentech Showcases New Clinical Data Across a Variety of Blood Diseases at American Society of Hematology 2016 Annual Meeting
BD Collaborates with JDRF to Focus on Extended Wear Innovations for Insulin Infusion Delivery
BD Launches First Syringe Designed for Use with Humulin® R U-500 Insulin
MDxHealth Announces Unique CPT Code Awarded for ConfirmMDx from the American Medical Association
BD MAX™ Vaginal Panel Receives FDA Market Authorization to Detect Most Common Causes of Vaginal Infections
Greenphire Receives EU-US Privacy Shield Certification
The 2016 Georges Mathé Prize Recognizes Research on the Immunological Determinants of the Response to Breast Cancer Treatment

Boost Your Social Network
& Crowdfunding Campaigns


LIFETIME SOCIAL MEDIA WALL
 
NewswireToday Celebrates 10 Years in Business
Find business coaching, life coaching, executive coaching and corporate coaching, best selling coaching books, ...



PREMIUM Members


Visit  JobsWare.com

Visit  Triggr & Bloom

Visit  NAKIVO, Inc.







 
  ©2016 PRZOOM — Limelon Advertising, Co.
Home | About PRZOOM | Advertise/Pricing | Contact | Investors | Privacy/TOS | Sitemap | FRANCAIS
newswire, PR free press releases distribution service magazines engine news alert newsroom press room breaking news public relations articles company news alerts newswiredistribution ezine bizentrepreneur biznewstoday digital business report market search pr firms agencies reports distri-bution today investor relation successful internet entrepreneur newswire distribution prtoday.com freenewswiredistribution asianewstoday bizwiretoday USA pr UK today