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SCHOTT Demonstrates syriQ™ InJentle Syringes for Biotech Drugs at Pharmapack North America - Rise in sensitive drug formulations requires new syringe concepts -
SCHOTT Demonstrates syriQ™ InJentle Syringes for Biotech Drugs at Pharmapack North America


PRZOOM - /newswire/ - Elmsford, NY, United States, 2014/06/10 - Rise in sensitive drug formulations requires new syringe concepts -

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SCHOTT will showcase its syriQ™ InJentle prefillable syringes at Pharmapack North America in New York on June 10-12, 2014 at booth #3466. These high-quality, prefillable glass syringes represent a superior delivery system for the increasingly advanced medicines developed by pharmaceutical companies, especially sensitive biotech drugs. syriQ InJentle’s unique design safely stores drugs and allows for easy administration in a continuing effort to ensure patient safety and health.

“In prefillable syringes, the drug is in contact with more materials than in other types of pharmaceutical primary packaging,” said Anil-Kumar Busimi, Head of Global Product Management Syringe Business at SCHOTT. “There’s contact with the glass, needle, needle glue, needle shield, plunger, and a silicone oil used as lubricant inside of the syringe barrel. With so many materials coming in contact with the drug, the chances of an interaction between the drug and syringe components increase dramatically, and the risk is even higher for sensitive biotech drugs. syriQ InJentle syringes, however, limit the contact materials to glass and rubber, equivalent to the materials drugs are exposed to when housed in vials. Through syriQ InJentle’s advanced design, SCHOTT has reduced this risk and is helping pharmaceutical companies improve their drugs and increase patient safety.”

syriQ InJentle syringes for drug stability
Biotech molecules tend to more easily interact with packaging due to their complex and sensitive makeup. With this in mind, SCHOTT designed syriQ InJentle to decrease the risk by reducing the number of materials and components the drug comes into contact with during storage.

Traces of tungsten, for example, which traditionally are found in glass syringes after the forming process, have been found to interact with some biotech molecules. SCHOTT’s new syringes are designed with a special geometry for the glass body that eliminates the use of a tungsten pin during the glass forming process so that syriQ InJentle is entirely tungsten-free.

Adhesives used for needle bonding could also be a potential source of leachables that could impact drug stability and efficacy. The design of syriQ InJentle syringes prevents the drug from coming into contact with the needle and the adhesive during storage to ensure drug stability.

Another substance critical to syringe functionality silicone oil is used to lubricate the inside of the syringe barrel to ensure smooth injection. However, silicone oil has been attributed to unexpected reactions with some biological drugs, leading to protein aggregation or an increase in subvisible particles. This is a new challenge for biotech drug developers. To solve this challenge, the syriQ InJentle barrel has baked-on silicone, which significantly reduces the interaction between the drug and the silicone while maintaining the functionality.

In an additional effort to ensure packaging and drug integrity, the syringe needle shield has a tamper-evident closure that indicates whether the syringe has been used. Yet this closure can be easily opened even after longer storage periods.

Thin and sharp needles for a more comfortable administration
Additionally, the syringe’s design ensures the needle does not stick into the needle shield, preserving the needle’s sharpness. This, combined with high-tech needle siliconization, leads to needles with a low penetration force. In fact, syriQ InJentle syringes can be offered with thin needles up to 32 gauge. This makes injections less painful for the patient.

SCHOTT syriQ InJentle syringes are ready for filling and packaged in common nests and tubs that can be integrated into existing filling lines. In the field of glass syringes, SCHOTT offers products ranging from 0.5 to 3 milliliters (ml) that are suitable for a variety of applications, such as heparin, vaccines, biotechnology, and special applications.

SCHOTT ( is an international technology group with 130 years of experience in the areas of specialty glass and materials and advanced technologies. SCHOTT ranks number one in the world with many of its products. Its core markets are the household appliance, pharmaceutical, electronics, optics and transportation industries. The company is strongly committed to contributing to its customers’ success and making SCHOTT an important part of people’s lives with high-quality products and intelligent solutions. SCHOTT is committed to managing its business in a sustainable manner and supporting its employees, society and the environment. The SCHOTT Group maintains close proximity to its customers with manufacturing and sales units in 35 countries. Its workforce of 15,400 employees generated worldwide sales of US$ 2.5 billion for the 2012/2013 fiscal year.

Press contact: Mike Lizun - Gregory FCA on behalf of SCHOTT
P: 610-642-1435 - E: mike[.]

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Agency / Source: SCHOTT North America


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SCHOTT Demonstrates syriQ™ InJentle Syringes for Biotech Drugs at Pharmapack North America

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syriQ™ InJentle Syringes | SCHOTT
Contact: Rina Della Vecchia - SCHOTT North America, Inc. 
914-831-2286 rina.dellavecchia[.]
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IMPORTANT INFORMATION: Issuance, publication or distribution of this press release in certain jurisdictions could be subject to restrictions. The recipient of this press release is responsible for using this press release and the information herein in accordance with the applicable rules and regulations in the particular jurisdiction. This press release does not constitute an offer or an offering to acquire or subscribe for any SCHOTT North America securities in any jurisdiction including any other companies listed or named in this release.

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