Free press releases distribution network?

Agency / Source: Mettler-Toledo, Inc.

Check Ads Availability|e-mail Article


Are you the owner of this article?, Turn it PREMIUM with your LOGO instead - and make it 3rd party Ads-Free! within the next hour!



Mettler-Toledo Unveils Innovative Optical Density Measurement System Protects Product from Contamination - A pharmaceutical manufacturer in Argentina faced the challenge of measuring the optical density of a sterile solution in-line without the possibility of product contamination - MT.com
Mettler-Toledo Unveils Innovative Optical Density Measurement System Protects Product from Contamination

 

PRZOOM - /newswire/ - Columbia, MD, United States, 2013/05/16 - A pharmaceutical manufacturer in Argentina faced the challenge of measuring the optical density of a sterile solution in-line without the possibility of product contamination - MT.com.

   
 
Your Banner Ad Here instead - Showing along with ALL Articles covering Manufacturing/Robotics Announcements

Replace these Affiliate Programs at ANYTIME! Your banner here within the next hour. Learn How!


 

METTLER TOLEDO developed a reliable solution that ensured sterility was not compromised, and which also reduced product loss.

Production of injectable corticoidsteroid
Química Montpellier S.A. is a pharmaceutical laboratory with production facilities in Buenos Aires, Argentina. In recent years, facilities and equipment at its manufacturing plant have been extensively refurbished, positioning it among the most modern pharmaceutical laboratories in South America. The company produces betamethasone injections, a corticoidsteroid used in the treatment of allergic reaction symptoms. For increased efficacy, the vials of betamethasone combine soluble and insoluble forms of the active drug.

Optical density determines active principle concentration
The concentration and uniformity of the insoluble form (acetate or dipropionate) is determined by measuring samples in the lab. This is a time-consuming operation and does not confirm uniformity throughout a batch. Química Montpellier technicians wanted a method of measuring the concentration of the insoluble form at the filling line in a continuous way to ensure dose uniformity, without any risk of product contamination.

As the only insoluble component of the formulation is the insoluble form of the active pharmaceutical ingredient (API), the optical density (OD) of the medium is proportional to the concentration of the API.

OD measurement through glass
METTLER TOLEDO, through its representative in Argentina, HITEC S.R.L realized that the betamethasone could be measured through glass by an OD sensor before entering the vials, therefore eliminating contact between the sensor and the solution. To achieve this would require redirecting the flow of betamethasone through a glass tube placed inside a specially developed housing.

After some research at HITEC's facility, a housing was developed that would hold a METTLER TOLEDO optical density sensor at the optimal angle and encase the glass tube to prevent unwanted light ingress that would affect measurement results. The system was installed and a test phase initiated. Results showed a very precise correlation between measurements from the new system and those obtained by the off-line method.

API concentration ensured
Benefits of this system are numerous: continuous real-time data, assurance of betamethasone uniformity in every finished vial, instant detection of out-of-spec bulk suspension (eliminating incorrectly filled vials, reducing product loss and increasing the overall yield per batch), PAT initiative compliance through enhancement of process understanding, and time and cost savings from reduced lab measurements.

Química Montpellier is more than satisfied with the OD system's performance. As well as the above benefits, technicians note that system maintenance is very low; the sensor rarely requires cleaning since coating and fouling do not occur.

About METTLER TOLEDO Process Analytics

METTLER TOLEDO's Process Analytics division (mt.com) develops and manufactures instrumentation and sensors used for process measurement and control, offering measurements of pH, dissolved and gaseous oxygen, dissolved ozone, turbidity, oxygen reduction potential, resistivity/conductivity, total organic carbon and flow.

 
 
Your Banner Ad Here instead - Showing along with ALL Articles covering Manufacturing/Robotics Announcements

Replace these Affiliate Programs at ANYTIME! Your banner here within the next hour. Learn How!


 

Agency / Source: Mettler-Toledo, Inc.

 
 

Availability: All Regions (Including Int'l)

 

Traffic Booster: [/] Quick PRZOOM - Press & Newswire Visibility Checker

 

Distribution / Indexing: [+] / [Company listed above is a registered member of our network. Content made possible by PRZOOM / PRTODAY indexing services]

 
 
# # #
 
 
  Your Banner Ad showing on ALL
Manufacturing/Robotics articles,
CATCH Visitors via Your Competitors Announcements!


Mettler-Toledo Unveils Innovative Optical Density Measurement System Protects Product from Contamination

Company website links NOT available to basic submissions
It is OK to republish and/or LINK any newswire for any legitimate media purpose as long as you name PRZOOM - Press & Newswire and LINK as the source.
 
  For more information, please visit:
Is this your article? Activate ALL web links by Upgrading to Press Release PREMIUM Plan Now!
Optical Density |
Contact: Marie-Louise Hupert - MT.com 
410-910-8486 epublicrelations[.]mt.com
 
PRZOOM / PRTODAY - Newswire Today disclaims any content contained in this article. If you need/wish to contact the company who published the current release, you will need to contact them - NOT us. Issuers of articles are solely responsible for the accuracy of their content. Our complete disclaimer appears here.
IMPORTANT INFORMATION: Issuance, publication or distribution of this press release in certain jurisdictions could be subject to restrictions. The recipient of this press release is responsible for using this press release and the information herein in accordance with the applicable rules and regulations in the particular jurisdiction. This press release does not constitute an offer or an offering to acquire or subscribe for any Mettler-Toledo, Inc. securities in any jurisdiction including any other companies listed or named in this release.

Manufacturing/Robotics via RSSAdd NewswireToday - PRZOOM Headline News to FeedBurner
Find who RetweetFollow @NewswireTODAY



Are you the owner of this article?, Turn it PREMIUM with your LOGO instead - and make it 3rd party Ads-Free! within the next hour!




Read Latest Press Releases From Mettler-Toledo, Inc. / Company Profile


Read Manufacturing/Robotics Most Recent Related Press Releases:

PPG Initiates Global Restructuring, Targeting $125 Million in Annual Savings
Local Manufacturing Offers Strong Growth Opportunities in the Thriving Nigeria and South Africa Cement Additives Markets Reports Frost & Sullivan
BASF Expands Automotive Refinish Coatings Manufacturing to Asia Pacific
Alstom’s South African JV Gibela Successfully Handed Over to PRASA The First X’Trapolis Mega
Neptune Lines Reduces Fuel Consumption and Emissions with Hempaguard
BASF Launches Ucrete MF40AS Industrial Flooring System on the European Market
Raritan Unveils Intelligent Cabinet Concept in Collaboration with Legrand Data Communications At Gartner Conference
Beretta Continues Global Celebration of its 490th Anniversary with Unveiling of One-of-a-Kind Shotgun in New York City
LANXESS Virkon S Proven to Kill Highly Pathogenic Avian Influenza Strains
BASF to Offer Tailor-made Product Innovation At European Coatings Show

Boost Your Social Network
& Crowdfunding Campaigns


LIFETIME SOCIAL MEDIA WALL
 
NewswireToday Celebrates 10 Years in Business
Find business coaching, life coaching, executive coaching and corporate coaching, best selling coaching books, ...



PREMIUM Members


Visit  La Bella Bakery Artisan Bakery Arizona

Visit  Triggr & Bloom

Visit  BizJobs.com







 
  ©2016 PRZOOM — Limelon Advertising, Co.
Home | About PRZOOM | Advertise/Pricing | Contact | Investors | Privacy/TOS | Sitemap | FRANCAIS
newswire, PR free press releases distribution service magazines engine news alert newsroom press room breaking news public relations articles company news alerts newswiredistribution ezine bizentrepreneur biznewstoday digital business report market search pr firms agencies reports distri-bution today investor relation successful internet entrepreneur newswire distribution prtoday.com freenewswiredistribution asianewstoday bizwiretoday USA pr UK today